The Number of Different Binary Functions Generated by NK-Kauffman Networks and the Emergence of Genetic Robustness

Abstract

We determine the average number (N, K) , of NK-Kauffman networks that give rise to the same binary function. We show that, for N 1 , there exists a connectivity critical value Kc such that (N,K) ≈ eφ N ( φ > 0 ) for K < Kc and (N,K) ≈ 1 for K > Kc . We find that Kc is not a constant, but scales very slowly with N , as Kc ≈ 2 2 (2N / 2) . The problem of genetic robustness emerges as a statistical property of the ensemble of NK-Kauffman networks and impose tight constraints in the average number of epistatic interactions that the genotype-phenotype map can have.

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