Line-Defect Patterns of Unstable Spiral Waves in Cardiac Tissue

Abstract

Spiral wave propagation in period-2 excitable media is often accompanied by line-defects, the locus of points with period-1 oscillations. Here we investigate spiral line-defects in cardiac tissue where period-2 behavior has a known arrhythmogenic role. We find that the number of line defects, which is constrained to be an odd integer, is three for a freely rotating spiral, with and without meander, but one for a spiral anchored around a fixed heterogeneity. We interpret analytically this finding using a simple theory where spiral wave unstable modes with different numbers of line-defects correspond to quantized solutions of a Helmholtz equation. Furthermore, the slow inward rotation of spiral line-defects is described in different regimes.