Statistical mechanics formulation of radiobiology

Abstract

The expression of survival factors for radiation damaged cells is empirical and based on probabilistic assumptions. We obtain it either from the maximum entropy principle for the classical Boltzmann-Gibbs entropy and/or from the Tsallis entropy. Empiric models are found to be particular cases of the obtained expression. The survival factor exhibits a phase transition behaviour. This formulation supports different tissues grouped as universality classes.

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