Multilayer of Phospholipid Membranes on a Hydrosol Substrate

Abstract

The molecular structure of a multilayer of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) adsorbed on the surface of the hydrosol of silica nanoparticles has been studied by the synchrotron radiation scattering method. According to the reflectometry data, the multilayer is formed by planar phospholipid bilayers with a thickness of 69 +/- 1 Angstrom and its total thickness is about 400 Angstrom. Grazing-incidence diffraction indicates that the bilayers are in the crystal state with an area of 41.6 +/- 0.7 Angstrom^2 per molecule.