Abnormal effective connectivity in migraine with aura under photic stimulation

Abstract

Migraine patients with aura show a peculiar pattern of visual reactivity compared with those of migraine patients without aura: an increased effective connectivity, connected to a reduced synchronization among EEG channels, for frequencies in the beta band. The effective connectivity is evaluated in terms of the Granger causality. This anomalous response to visual stimuli may play a crucial role in the progression of spreading depression and clinical evidences of aura symptoms.

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