Migration-selection balance at multiple loci and selection on dominance and recombination

Abstract

A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at equilibrium, and that all immigrant genes will eventually be eliminated by selection, the population structure can be inferred explicitly from the deterministic branching process taking place within a single immigrant lineage. Unless the migration and recombination rates were high, this simple method was a very close approximation to the simulated migration-selection balance with all possible multilocus genotypes considered.