Single Channel Cutaneous Electrogastrography Parameters from Local White Rabbit (Oryctolagus cuniculus)

Abstract

EGG recordings performed on 13 local white rabbits (O. cuniculus) which divided into 3 groups; acetosal 35 mg/kgBM receiver, reserpine 37.5 mg/kgBM receiver, and control group. A total of 72 EGG recordings obtained from them, which divided furthermore into 9 datasets based on prepandrial state, postpandrial state, and post 1 hour drug administration state. EGG parameters such as the number of cycle per minute ($cpm$), average voltage of action potential segment ($\bar{V_a}$), root mean square voltage of action potential segment ($A_{rms}$), root mean square voltage of all EGG segment ($V_{rms}$), average period of action potential segment ($\bar{T_a}$), average period of resting plateau ($\bar{T_i}$), average period difference among action potential segment and resting plateau ($\bar{T_a - T_i}$), and dominant frequency ($f_d$) are obtained. Insignificant difference of $f_d$ ($P$ = 0.9112993) and cpm ($P$ = 0.9382463) among 9 EGG datasets were found. These findings contrasted the common practice of EGG assessment, which $f_d$ and $cpm$ are the main parameters for diagnosis base. In other hand, significant difference between 9 EGG datasets found for $\bar{V_a}$, $A_{rms}$, and $V_{rms}$ parameter with $P$ = 0.0007346, 0.0039191, and 0.0000559 respectively. In conclusion, EGG parameterization should not be limited to $f_d$ and $cpm$ only.