A Model for Emergence of Multiple Anti-Microbial Resistance in a Petri Torus
Abstract
This work introduces a new statistical physics lattice model of bacteria interacting with anti-microbial drugs that can reproduce qualitative features of resistance emergence and whose model parameters and outputs can be measured with controlled in vitro experiments. The lattice is inhabited by agents modeled by Ising perceptrons. The results show the advantage of mixing drugs among the population compared to other treatment protocols.
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