IGLOSS: iterative gapless local similarity search

Abstract

Searching for local sequence patterns is one of the basic tasks in bioinformatics. Sequence patterns might have structural, functional or some other relevance, and numerous methods have been developed to detect and analyze them. These methods often depend on the wealth of information already collected. The explosion in the number of newly available sequences calls for novel methods to explore local sequence similarity. We have developed a high sensitivity web-based iterative local similarity scanner, that finds sequence patterns similar to a submitted query.