Resting-state ASL : Toward an optimal sequence duration

Abstract

Resting-state functional Arterial Spin Labeling (rs-fASL) in clinical daily practice and academic research stay discreet compared to resting-state BOLD. However, by giving direct access to cerebral blood flow maps, rs-fASL leads to significant clinical subject scaled application as CBF can be considered as a biomarker in common neuropathology. Our work here focuses on the link between overall quality of rs-fASL and duration of acquisition. To this end, we consider subject self-Default Mode Network (DMN), and assess DMN quality depletion compared to a gold standard DMN depending on the duration of acquisition.