Generating protein sequences from antibiotic resistance genes data using Generative Adversarial Networks

Abstract

We introduce a method to generate synthetic protein sequences which are predicted to be resistant to certain antibiotics. We did this using 6,023 genes that were predicted to be resistant to antibiotics in the intestinal region of the human gut and were fed as input to a Wasserstein generative adversarial network (W-GAN) model a variant to the original generative adversarial model which has been known to perform efficiently when it comes to mimicking the distribution of the real data in order to generate new data which is similar in style to the original data which was fed as the training data