Quantitative analysis of the dynamics of maternal gradients of the early Drosophila embryo
Abstract
The predetermination, formation and maintenance of the primary morphogenetic gradient (bicoid gradient) of the early Drosophila embryo involves many interrelated processes. Here we focus on a system-biological analysis of the processes of redistribution of bicoid mRNA in an early embryo. The results of a quantitative analysis of experimental data, together with the results of their dynamic modeling, substantiate the role of active transport in the redistribution of bicoid mRNA.
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