Polynomials under Ornstein-Uhlenbeck noise and an application to inference in stochastic Hodgkin-Huxley systems

Abstract

We discuss estimation problems where a polynomial is observed under Ornstein Uhlenbeck noise over a long time interval. We prove local asymptotic normality (LAN) and specify asymptotically efficient estimators. We apply this to the following problem: feeding noise into the classical (deterministic) Hodgkin Huxley model of neuroscience, we are interested in asymptotically efficient estimation of the parameters of the noise process.