Hidden energy flows in strongly coupled nonequilibrium systems

Abstract

Quantifying the flow of energy within and through fluctuating nanoscale systems poses a significant challenge to understanding microscopic biological machines. A common approach involves coarse-graining, which allows a simplified description of such systems. This has the side effect of inducing so-called hidden contributions (due to sub-resolution dynamics) that complicate the resulting thermodynamics. Here we develop a thermodynamically consistent theory describing the nonequilibrium excess power internal to autonomous systems, and introduce a phenomenological framework to quantify the hidden excess power associated with their operation. We confirm our theoretical predictions in numerical simulations of a minimal model for both a molecular transport motor and a rotary motor.