Automatic Myocardial Disease Prediction From Delayed-Enhancement Cardiac MRI and Clinical Information

Abstract

Delayed-enhancement cardiac magnetic resonance (DE-CMR)provides important diagnostic and prognostic information on myocardial viability. The presence and extent of late gadolinium enhancement (LGE)in DE-CMR is negatively associated with the probability of improvement in left ventricular function after revascularization. Moreover, LGE findings can support the diagnosis of several other cardiomyopathies, but their absence does not rule them out, making disease classification by visual assessment difficult. In this work, we propose deep learning neural networks that can automatically predict myocardial disease from patient clinical information and DE-CMR. All the proposed networks achieve very good classification accuracy (>85%). Including information from DE-CMR (directly as images or as metadata following DE-CMR segmentation) is valuable in this classification task, improving the accuracy to 95-100%.