Efficient computational algorithms for approximate optimal designs

Abstract

In this paper, we propose two simple yet efficient computational algorithms to obtain approximate optimal designs for multi-dimensional linear regression on a large variety of design spaces. We focus on the two commonly used optimal criteria, $D$- and $A$-optimal criteria. For $D$-optimality, we provide an alternative proof for the monotonic convergence for $D$-optimal criterion and propose an efficient computational algorithm to obtain the approximate $D$-optimal design. We further show that the proposed algorithm converges to the $D$-optimal design, and then prove that the approximate $D$-optimal design converges to the continuous $D$-optimal design under certain conditions. For $A$-optimality, we provide an efficient algorithm to obtain approximate $A$-optimal design and conjecture the monotonicity of the proposed algorithm. Numerical comparisons suggest that the proposed algorithms perform well and they are comparable or superior to some existing algorithms.