Applications of PDEs and Stochastic Modeling to Protein Transport in Cell Biology

Abstract

Intracellular transport processes are essential to the healthy development of many organisms as well as more generally to healthy cellular function. The complex dynamics and interactions between protein molecules and filaments on different time and spatial scales generate many opportunities for mathematical modeling and analysis that can provide insights into protein sorting and overall cellular organization. Systems of advection-reaction-diffusion partial differential equations and stochastic state-switching particle models are especially useful in understanding spatiotemporal protein dynamics inside cells.