Sensitivity Analysis for Marginal Structural Models

Abstract

We introduce several methods for assessing sensitivity to unmeasured confounding in marginal structural models; importantly we allow treatments to be discrete or continuous, static or time-varying. We consider three sensitivity models: a propensity-based model, an outcome-based model, and a subset confounding model, in which only a fraction of the population is subject to unmeasured confounding. In each case we develop efficient estimators and confidence intervals for bounds on the causal parameters.