Enhancing Clinical Evidence Recommendation with Multi-Channel Heterogeneous Learning on Evidence Graphs

Abstract

Clinical evidence encompasses the associations and impacts between patients, interventions (such as drugs or physiotherapy), problems, and outcomes. The goal of recommending clinical evidence is to provide medical practitioners with relevant information to support their decision-making processes and to generate new evidence. Our specific task focuses on recommending evidence based on clinical problems. However, the direct connections between certain clinical problems and related evidence are often sparse, creating a challenge of link sparsity. Additionally, to recommend appropriate evidence, it is essential to jointly exploit both topological relationships among evidence and textual information describing them. To address these challenges, we define two knowledge graphs: an Evidence Co-reference Graph and an Evidence Text Graph, to represent the topological and linguistic relations among evidential elements, respectively. We also introduce a multi-channel heterogeneous learning model and a fusional attention mechanism to handle the co-reference-text heterogeneity in evidence recommendation. Our experiments demonstrate that our model outperforms state-of-the-art methods on open data.