Investigation of the ability to detect electrolyte disorder using PET with positron annihilation lifetime spectroscopy

Abstract

Various concentrations (8{\div}300 mmol/L) of NaCl, KCl and NaCl + KCl aqueous solutions were investigated using the positron annihilation lifetime spectroscopy (PALS). A strong dependence of the o-Ps intensity as a function of solution concentration was demonstrated. On this basis, the mean positron lifetime or the sum of counts in a selected time interval were proposed as reliable parameters for detecting disturbances in the ion balance of living organisms. The use of these parameters differentiating healthy and cancerous tissues is possible in a new generation of PET scanners equipped with a PALS detection module.