Synthesizing 3D computed tomography from MRI or CBCT using 2.5D deep neural networks

Abstract

Deep learning techniques, particularly convolutional neural networks (CNNs), have gained traction for synthetic computed tomography (sCT) generation from Magnetic resonance imaging (MRI), Cone-beam computed tomography (CBCT) and PET. In this report, we introduce a method to syn-thesize CT from MRI or CBCT. Our method is based on multi-slice (2.5D) CNNs. 2.5D CNNs offer distinct advantages over 3D CNNs when dealing with volumetric data. In the experiments, we evaluate the performance of our method for two tasks, MRI-to-sCT and CBCT-to-sCT generation. Target organs for both tasks are brain and pelvis.