Reusable Surrogate Models for Distillation Columns

Abstract

Surrogate modeling is a powerful methodology in chemical process engineering, frequently employed to accelerate optimization tasks where traditional flowsheet simulators are computationally prohibitive. However, the state-of-the-art is dominated by surrogate models trained for a narrow range of fixed chemical systems and operating conditions, limiting their reusability. This work introduces a paradigm shift towards reusable surrogates by developing a single model for distillation columns that generalizes across a vast design space. The key enabler is a novel ML-fueled modelfluid representation which allows for the generation of datasets of more than $1,000,000$ samples. This allows the surrogate to generalize not only over column specifications but also over the entire chemical space of homogeneous ternary vapor-liquid mixtures. We validate the model's accuracy and demonstrate its practical utility in a case study on entrainer distillation, where it successfully screens and ranks candidate entrainers, significantly reducing the computational effort compared to rigorous optimization.