Preparation Methods and Applications of Biomimetic Membranes

Abstract

Model biomembrane systems play a crucial role in advancing biomedical research by providing simplified yet effective platforms for exploring complex biological mechanisms. These systems span a wide range of scales, from single-molecule-thick lipid monolayers to micron-sized giant unilamellar vesicles. Their efficacy and applicability largely depend on selecting an optimal model and an appropriate synthesis process. This chapter offers a comprehensive description of conventional synthesis techniques, highlighting their limitations across various model membrane systems. Additionally, it provides an overview of biophysical studies on biomimetic membranes and explores key biological applications, including drug delivery, membrane-protein interactions, and biosensing.