Operator learning for models of tear film breakup

Abstract

Tear film (TF) breakup is a key driver of understanding dry eye disease, yet estimating TF thickness and osmolarity from fluorescence (FL) imaging typically requires solving computationally expensive inverse problems. We propose an operator learning framework that replaces traditional inverse solvers with neural operators trained on simulated TF dynamics. This approach offers a scalable path toward rapid, data-driven analysis of tear film dynamics.