Icosahedral packing of RNA viral genomes

Abstract

Recent studies reveal that certain viruses package a portion of their genome in a manner that mirrors the icosahedral symmetry of the protein container, or capsid. Graph theoretical constraints forbid exact realization of icosahedral symmetry. This paper proposes a model for the determination of quasi-icosahedral genome structures and discusses the connection between genomic structure and viral assembly kinetics.

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