Hierarchic Theory of Condensed Matter: Role of water in protein dynamics, function and cancer emergency
Alex Kaivarainen
Abstract
1. Role of inter-domain water clusters in large-scale dynamics of proteins; 2. Description of large-scale dynamics of proteins based on generalized Stokes-Einstein and Eyring-Polany equation; 3. Dynamic model of protein-ligand complexes formation; 4. The life-time of quasiparticles and frequencies of their excitation; 5. Mesoscopic mechanism of enzyme catalysis; 6. The mechanism of ATP hydrolysis energy utilization in muscle contraction and protein polymerization; 7. Water activity as a regulative factor in the intra- and inter-cell processes; 8. Water and cancer.
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