A Unified Framework for Heterogeneity, Contamination, and Missing Data in Multivariate Regression
Hung Tong, Cristina Tortora, Antonio Punzo
Abstract
Missing values, atypical observations, and heterogeneity across latent groups are common sources of complexity in regression data. The contaminated Gaussian cluster-weighted model (CG-CWM) provides a natural framework for handling atypical observations, including outliers and leverage points, in model-based clustering. We extend the CG-CWM to data with missing-at-random (MAR) values in both the response and covariate spaces. The proposed model provides clustering in regression analysis while distinguishing typical observations, outliers, and good and bad leverage points. By treating covariates as random, the model preserves assignment dependence, allowing them to contribute directly to cluster formation. Maximum likelihood estimation is performed through an expectation-conditional maximization (ECM) algorithm that accounts for four sources of incomplete information: missing responses and covariates, unknown component memberships, and latent contamination indicators. Conditional on these indicators, the joint distribution of responses and covariates is multivariate Gaussian, yielding closed-form conditional distributions for missing values and incorporating missingness uncertainty directly into parameter updates. Thus, missing values are handled within model fitting rather than by preliminary imputation. The framework provides clustering, clusterwise regression, model-based treatment of MAR values, and detection of atypical observations. Performance is assessed through numerical studies under varying levels of contamination and missingness patterns, and a real data application.
Create a lesson
Related papers
RECaST-Surv: A Calibrated Borrowing Method for Survival Endpoints in Unequal Randomized Trials
Dehua Bi, Arlina Shen, Ruben P. A. van Eijk et al.
Beyond Pretrends: A Discordance-Based Sensitivity Analysis for Difference-in-Differences
Thomas Leavitt
Earth and space observations meet complex algebras: from complex to octonions for multivariate autoregressive time series analysis
Susana Eyheramendy, Felipe Elorrieta, Wilfredo Palma et al.
Efficient transport and generalization of survival treatment effects
Axel Martin, Iván Díaz, Michele Santacatterina
A new tractable Archimedean copula for full-range tail dependence
Lei Hua
Doubly valid and doubly sharp sensitivity analysis to unobserved confounding for survival outcomes
Jean-Baptiste Baitairian, Bernard Sebastien, Rana Jreich et al.