Process Pathway Inference via Time Series Analysis
Chris Wiggins, Ilya Nemenman
Abstract
Motivated by recent experimental developments in functional genomics, we construct and test a numerical technique for inferring it process pathways, in which one process calls another process, from time series data. We validate using a case in which data are readily available and formulate an extension, appropriate for genetic regulatory networks, which exploits Bayesian inference and in which the present--day undersampling is compensated for by prior understanding of genetic regulation.
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