Inference of a nonlinear stochastic model of the cardiorespiratory interaction
V. N. Smelyanskiy, D. G. Luchinsky, A. Stefanovska, P. V. E. McClintock
Abstract
A new technique is introduced to reconstruct a nonlinear stochastic model of the cardiorespiratory interaction. Its inferential framework uses a set of polynomial basis functions representing the nonlinear force governing the system oscillations. The strength and direction of coupling, and the noise intensity are simultaneously inferred from a univariate blood pressure signal, monitored in a clinical environment. The technique does not require extensive global optimization and it is applicable to a wide range of complex dynamical systems subject to noise.
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