Solvent content of protein crystals from diffraction intensities by Independent Component Analysis
Antonio Lamura, Massimo Ladisa, Giovanni Nico, Dritan Siliqi
Abstract
An analysis of the protein content of several crystal forms of proteins has been performed. We apply a new numerical technique, the Independent Component Analysis (ICA), to determine the volume fraction of the asymmetric unit occupied by the protein. This technique requires only the crystallographic data of structure factors as input.
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