Lattice analogy of area-difference elasticity model for lipid-detergent bilayer vesiculation
Abstract
The vesiculation process was examined in the lipid-detergent solution (dimyristoyl-sn-glycero-phoshatidylcholine/octaethylleneglycol n-dodecyl ether/water), using small-angle neutron scattering experiments 1. When observing vesiculation proceeds from rod-like micelles to unilamellar vesicles, the transformation is induced by jump-like temperature increase and a monotonic increase in detergent concentration. Our numerical estimations of the vesicle shape parameters (the elasticity coefficients and its fraction on a macroscopic scale) are based upon the area-difference elasticity model 2, 3. Thus, we composed the numerical Monte Carlo method, which connects the macroscopic and microscopic scales by the concept of self-avoiding random surfaces.
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