A Model for Predicting Magnetic Particle Capture in a Microfluidic Bioseparator
E. P. Furlani, Y. Sahoo, K. C. Ng, J. C. Wortman, T. E. Monk
Abstract
A model is presented for predicting the capture of magnetic micro/nano-particles in a bioseparation microsystem. This bioseparator consists of an array of conductive elements embedded beneath a rectangular microfluidic channel. The magnetic particles are introduced into the microchannel in solution, and are attracted and held by the magnetic force produced by the energized elements. Analytical expressions are obtained for the dominant magnetic and fluidic forces on the particles as they move through the microchannel. These expressions are included in the equations of motion, which are solved numerically to predict particle trajectories and capture time. This model is well-suited for parametric analysis of particle capture taking into account variations in particle size, material properties, applied current, microchannel dimensions, fluid properties, and flow velocity.
Create a lesson
Related papers
A Variational Framework for Nonlinear Chemical Thermodynamics Employing the Maximum Energy Dissipation Principle
Adam Moroz
Retrievable but Unencountered: The Missing Exposure Denominator in Large Academic Ebook Collections
Jette Veenstra, Mauricio Munoz Arias
Where Energy Is Spent Sets the Depth of Kinetic Proofreading
Uğur Çetiner
On the Role of Dispersion in One Model of Propagation of Elastic Excitations in Nerves
Alexander I. Kozlov
Quantifying the Biophysical Properties of Red Blood Cells in Gaucher Disease
Zhaojie Chai, Marine de Person, Pierre A. Buffet et al.
Roles of vortices and turbulent eddies in particle preferential concentration and deposition in the human respiratory tract
Mengtao Li, Yawei Wang, Wentao Feng et al.